The Jane Coffin Childs Memorial Fund for Medical Research

Historical Funder

New Haven, Connecticut · EIN 06-6034840 · Private foundation · Website

Grants paid (2024)$4.1M

Organizations funded58

Typical grant$74,000

Total assets$60M

Half of its grants to organizations were between $73,800 and $76,000.

From the return

How to apply

The foundation filed the following application information (Form 990-PF Part XV, tax year 2024):

Contact	ANITA PEPPER
Address	333 CEDAR STREET SHM L300, NEW HAVEN CT 06510
Phone	2037854612
Form and materials	FORMAL WRITTEN APPLICATION OUTLINING PROPOSAL AND PREVIOUS WORK EXPERIENCE.
Deadlines	FEBRUARY 1ST OF EACH YEAR.
Restrictions	POST DOCTORAL FELLOWSHIPS FOR CANDIDATES WHO PERFORM CANCER RESEARCH.

Copied as filed. Deadlines on a tax return describe the foundation's usual process; they are not confirmation of a current open cycle.

What it funds

Share of grant lines on the latest return, classified from the purpose each grant states.

Education16
Health8
STEM3
Animal Welfare1

Where it gives

98% of grants went outside Connecticut.

Grants paid in tax year 2024

Recipient	Location	Purpose	Amount
Harvard University Medical School	Boston, MA	In Vivo tracking of G protein-coupled receptors sensing for gut metabolites	$114,000
Stanford University	Stanford, CA	Examining the neural mechanisms for generalization	$113,000
University of Washington	Seattle, WA	Mechanisms of Immune Memory Generation in a Native RNA Targeting CRISPR System	$113,000
University of Washington	Seattle, WA	Evaluating neuromodulatory networks across brain states	$112,667
University of California Berkeley	Berkeley, CA	An unprecedented atomistic picture of contranslational protein folding	$112,000
California Institute of Technology	Pasadena, CA	Synthetic protein circuits a conditional triggers of anti-tumor immunity	$107,417
Princeton University	Princeton, NJ	Main-Group Chemoproteomic Platforms for Deciphering and Drugging Methionine	$106,667
Columbia University	New York, NY	Neuronal and immunological dissection of antidepresant responsiveness	$106,000
University of California San Francisco	San Francisco, CA	Ovulation of the fittest	$106,000
University of California San Francisco	San Francisco, CA	Evolution of human-specific neuronal activity-dependent gene regulation	$106,000
Broad Institute of MIT and Harvard	Cambridge, MA	A DNA-encoded library strategy for molecular glue discovery	$78,000
University of California San Francisco	San Francisco, CA	Uncovering the functional architecture of the human speech cortex	$78,000
Columbia University	New York, NY	Learning the modular grammar of phase separation in signaling networks	$76,000
Stowers Institute for Medical Research	Kansas City, MO	Determine how ribosome heterogeneity regulates early embyrogenesis	$76,000
The Rockefeller University	New York, NY	Unraveling lipid transport across the mycobacterial cell envelope	$76,000
University of California Berkeley	Berkeley, CA	Exploring mechanisms for flexible learning in higher-order neural circuits	$75,000
University of California Berkeley	Berkeley, CA	Structural basis of Doa10-mediated protein quality control at the ER	$75,000
Max Planck Institute of Immunobiology & Epigenetic	Mnchen, GM	Direct Visualization of DNA Methyltransferase Oligomerization and Its Influence on Neuronal Gene Regulation	$74,800
Boston Medical Center Corporation	Boston, MA	Manipulating vascular endocytosis to direct blood and immune cell migration	$74,000
Broad Institute of MIT and Harvard	Cambridge, MA	Deciphering the Molecular Mechanisms of Alternative Splicing Regulation via Intronic Transposable Elements	$74,000
Duke University	Durham, NC	Dissecting the Dynamics of Tissue Patterning During Regeneration	$74,000
Duke University	Durham, NC	Determining how basement membranes stretch and recover to support tissues	$74,000
Harvard University	Cambridge, MA	How to build (and rebuild) an animal	$74,000
Harvard University	Cambridge, MA	Molecular basis of sensory integration in octopus	$74,000
Johns Hopkins University School of Medicine	Baltimore, MD	Using single cell transcriptomics to understand homeostatic sleep pressure	$74,000
Massachusetts General Hospital	Boston, MA	In situ cryoET analysis of cristae biogenesis and morphology	$74,000
Massachusetts Institute of Technology	Cambridge, MA	Central control of the autonomic nervous system in chronic pain and anxiety	$74,000
Niaid	Bethesda, MD	Sexual recombination and virulence in the success of African trypanosomes	$74,000
University of Minnesota	Mineapolis, MN	Effects of regulatory network divergence on drug resistance in Candida	$74,000
University of Utah	Salt Lake City, UT	Classification of exotic ATPase functions using large language models	$74,000
California Institute of Technology	Pasadena, CA	Defining the role of protein homeostasis in spermatogenesis	$73,800
Gladstone Institutes	San Francisco, CA	The molecular biology of Obelisk RNAs	$73,800
Harvard University	Cambridge, MA	Secretory cell innovation in a symbiotic interaction	$73,800
Harvard University	Cambridge, MA	Learning structure in genotype to phenotype maps	$73,800
Massachusetts Institute of Technology	Cambridge, MA	LIGHTing up tumor-associated tertiary lymphoid structures through cytokine pharmacokinetic engineering	$73,800
Massachusetts Institute of Technology	Cambridge, MA	Understanding tissue damage in the pre-neoplasia to neoplasia shift of colorectal cancer	$73,800
Memorial Sloan Kettering Cancer Center	New York, NY	Mechanisms and consequences of APOBEC3 targeting of extrachromosomal DNA	$73,800
Oregon Health and Science University	Portland, OR	Mechanisms of Type I PARP1 Inhibitors in Regulating Cell Fate Decisions in Cancer	$73,800
Princeton University	Princeton, NJ	Hormone-mediated changes in neural computations that drive flexible social behaviors	$73,800
Stanford University	Stanford, CA	Decoding Aging Neurogenic Niches: Unraveling Somatic Mutations, Clonal Dynamics, and Functional Decline	$73,800
The Scripps Research Institute	La Jolla, CA	Illuminating cryptic functional pockets in the human proteome with electrophilic stereoprobes	$73,800
The University of Texas at Austin	Austin, TX	Structure-based vaccine design targeting mpox antigen A27	$73,800
University of Utah	Salt Lake City, UT	Ron Tyrosine Kinase deficiency uncovers a critical regulator of anti-tumor T Cell responses	$73,800
Yale University	New Haven, CT	Novel Chemical Tools for Targeted Eradication of DNA Repair Proteins and Application to Chemosensitization	$73,800
University of Michigan	Ann Arbor, MI	Interplay of spatial structure and collective drug resistance across scale	$57,500
The Scripps Research Institute	La Jolla, CA	Timing biomolecular interactions in massively high throughput via a polymerase stopwatch	$49,333
The Rockefeller University	New York, NY	Understanding how the whole becomes more than the sum of its parts: Linking subcellular processes to emergent supracellular patterns	$44,633
The Scripps Research Institute	La Jolla, CA	Towards a novel tauopathy therapeutic: harnessing biomolecular condensates for targeted protein degradation	$41,800
Brandeis University	Waltham, MA	Timing molecular interactions in high throughput via a polymerase stopwatch	$39,000
Harvard University	Cambridge, MA	Neural mechanisms of taste and visceral signal integration in the brainstem	$37,500
Boston Children's Hospital	Boston, MA	Dissecting the impact of non-coding somatic mutations in the human brain	$37,000
Harvard University	Cambridge, MA	Reconstruct cell trajectories and communications in brain development	$37,000
Johns Hopkins University	Baltimore, MD	Defining regulatory principles of translation during nutrient shifts	$30,883
National Institue of HealthNICHD	Bethesda, MD	Linking Parts to Process: Probing the Cell-Biological Basis for Tissue Patterning in Developing Mesenchyme	$29,167
University of California Berkeley	Berkeley, CA	Discovery and Synthesis of novel anticancer drugs via enzyme engineering	$12,334
Dana Farber Cancer Institute	Boston, MA	Mechanisms and consequences of LINE-1-mediated genome instability	$12,333
Harvard University	Cambridge, MA	The evolution of complex chemosensation	$12,333
University of California Berkeley	Berkeley, CA	Main-group platforms for deciphering and drugging metionine	$4,200

Grants approved for future payment

Recipient	Location	Purpose	Amount
Cincinnati Children's Hospital	Cincinnati, OH	Multifunctional RNA-binding transcription factors coordinate cell states in development	$0
Gladstone Institutes	San Francisco, CA	Engineering CAR T cells for Enhanced Cancer Immunotherapy via Protein Interaction Network Analysis	$0
Harvard Medical School	Boston, MA	Organisational logic of the spino-parabrachial pathway for light touch	$0
Massachusetts General Hospital	Boston, MA	A spatial stochasticity theory resolves how host-protective T cell responses emerge amid regulatory T cell immunosuppression	$0
Massachusetts Institute of Technology	Cambridge, MA	Illuminating the cell envelope architecture and assembly of a tick-borne pathogen	$0
Massachusetts Institute of Technology	Cambridge, MA	Role of neoantigen-nonspecific Passenger T cells in cancer-associated immunity and tumor progression	$0
Memorial Sloan Kettering Cancer Center	New York, NY	Understanding how bacteria-bacteria interactions influence antibiotic resistance in a microbiome context	$0
Memorial Sloan Kettering Cancer Center	New York, NY	Recording cell states and signaling events to reveal cell fate decisions during pancreatic islet differentiation	$0
Princeton University	Princeton, NJ	Biochemical basis and function of lipid spatial localization within the brain	$0
Stanford University	Stanford, CA	Deciphering the Role of EBV-Infected B Cells and Autoimmunity in Post-Infectious Syndromes and Developing a Targeted Elimination Strategy	$0
The Rockefeller University	New York, NY	A genetic approach to study metabolite sensing and regulation in organelles	$0
University of California San Francisco	San Francisco, CA	Neuronal mechanisms of simulations in the brain of sleeping mice	$0
University of California Berkeley	Berkeley, CA	Harnessing long-range hormone signaling for therapeutic delivery	$0
University of Colorado Boulder	Boulder, CO	Unlocking the Bacterial Vault: Novel Organelles Involved in RNA Repair	$0
University of Utah	Salt Lake City, UT	The early-life microbiome regulates BETA-cell function and type-1 diabetes via gamma-aminobutyric acid	$0
University of Washington	Seattle, WA	"Healthy aneuploidy": Discovering strategies from the placenta to regulate aneuploidy tolerance	$0
University of Washington	Seattle, WA	Investigation of immune systems in multicellular bacteria	$0
University of Washington	Seattle, WA	Decoding the Structural Basis of Immunogenicity	$0
Vanderbilt University Medical Center	Nashville, TN	Defining the targets of the antibody response to natural Oropouche virus infection	$0
Washington University in St Louis	St Louis, MO	Structural mechanisms for higher-order microtubule assembly function in parasites	$0
Washington University in St Louis	St Louis, MO	The functional role of transposable element-derived transcripts in cancer progression	$0

Giving by year

Tax year	Grants paid	Grant lines
2024	$4,071,767	79
2023	$4,009,655	81
2022	$3,170,251	79

Sources

IRS Form 990-PF, tax year 2024, filed Feb 20, 2026 - IRS e-file batch, object ID 202630519349100208
IRS Tax Exempt Organization Search for EIN 06-6034840
Profile updated Nov 5, 2026

Facts on this page come from the foundation's own IRS Form 990-PF filings as published by the IRS. Grantvello does not know whether a foundation is accepting proposals right now: a past grant is not an open opportunity. Always confirm current guidelines with the funder before applying.