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NIOSH Exploratory/Developmental Grant Program (R21)

Upcoming

Centers for Disease Control and Prevention - ERA · Opportunity number RFA-OH-27-033 · Forecast

Expected postingDec 16, 2026
Closing dateFeb 16, 2027
Award ceiling$300,000
Expected awards10

Closing date explanation: for New Applications; Standard Due Dates apply for future dates. All applications must be submitted no later than 11:59 pm local time of the applicant organization.

From Grants.gov

Eligibility

Nonprofits are listed as eligible applicants.

  • Private institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Native American tribal governments (Federally recognized)
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses
  • City or township governments
  • County governments
  • State governments
  • Public and state controlled institutions of higher education
  • Small businesses
  • Independent school districts
  • Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Description

The R21 grant program is designed to advance our understanding of occupational diseases and injuries by focusing on the following three objectives:

• Identify the risks and conditions linked to workplace health issues.

• Develop strategies to reduce risks and limit exposure to hazardous environments.

• Translate significant scientific discoveries into prevention measures and products that can effectively reduce work-related illnesses and injuries. The National Institute for Occupational Safety and Health (NIOSH) actively supports exploratory and developmental research projects (R21) that pursue:

• Innovative scientific concepts.

• New model systems.

• Tools or technologies with the potential to make a meaningful impact on occupational safety and health. Through this NOFO, applicants will:

• Provide a clear and concise description of the specific occupational health burden the proposal addresses.

• Demonstrate how the proposed research activities will lead to outputs that directly contribute to alleviating this burden.

• Outline the expected outcomes and impacts of their research during the project and in the long term.

Funding

Total program funding$3,000,000
Award floorNot listed
Award ceiling$300,000
CategoryHealth
Assistance listing93.262

Official sources

Last verified on Grants.gov Nov 4, 2026. Grantvello is not affiliated with Grants.gov or Centers for Disease Control and Prevention - ERA. The notice on Grants.gov is the binding text.