Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI)

  Air Force Office of Scientific Research · NOFOAFRLAFOSR20260002

  Open
  Closes Apr 9, 2027 Award up to $15,000,000 Program total $170M

• EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows

  U.S. National Science Foundation · 24-528

  Open
  Closes Apr 13, 2027 Program total $15M

• IUSE / Professional Formation of Engineers: Revolutionizing Engineering Departments (IUSE/PFE: RED)

  U.S. National Science Foundation · 24-564

  Open
  Closes Apr 13, 2027 Award up to $2,000,000 Program total $8M

• Findable Accessible Interoperable Reusable Open Science (FAIROS)

  U.S. National Science Foundation · 25-533

  Open
  Closes Apr 14, 2027 Program total $6M

• Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-131

  Open
  Closes Apr 15, 2027 Award up to $250,000 Program total $250K

• Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)

  National Institutes of Health · PA-24-201

  Open
  Closes Apr 18, 2027

• Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

  National Institutes of Health · RFA-ES-25-002

  Open
  Closes Apr 20, 2027

• Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks

  Golden Field Office · DE-FOA-0003648

  Open
  Closes Apr 26, 2027

• NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)

  National Institutes of Health · RFA-HL-26-002

  Open
  Closes Apr 28, 2027

• NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)

  National Institutes of Health · RFA-HL-26-003

  Open
  Closes Apr 28, 2027

• LPS Qubit Collaboratory (LQC)

  Dept of the Army -- Materiel Command · W911NF21S0009

  Open
  Closes Apr 30, 2027

• F26AS00105 National Fish Passage Program

  Fish and Wildlife Service · F26AS00105

  Open
  Closes Apr 30, 2027 Award up to $1,000,000 Program total $15M

• Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)

  National Institutes of Health · PAR-26-001

  Open
  Closes May 7, 2027

• Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

  National Institutes of Health · PA-24-191

  Open
  Closes May 7, 2027

• NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)

  National Institutes of Health · PA-24-193

  Open
  Closes May 7, 2027

• New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)

  National Institutes of Health · PAR-25-272

  Open
  Closes May 7, 2027

• New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-279

  Open
  Closes May 7, 2027

• Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)

  National Institutes of Health · PA-24-190

  Open
  Closes May 7, 2027

• NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-143

  Open
  Closes May 7, 2027

• Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

  National Institutes of Health · PA-24-185

  Open
  Closes May 7, 2027

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.