Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

824 open, 304 upcoming · last checked Nov 4, 2026 · 1,128 shown by this search.

• Fiscal Year (FY) 2027 Department of War (DoW) Defense University Research Instrumentation Program (DURIP)

  Dept of the Army -- Materiel Command · W911NF26S0095

  Open
  Closes Nov 6, 2026 Award up to $3,000,000 Program total $28M

• Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)

  National Institutes of Health · RFA-DK-27-125

  Open
  Closes Nov 6, 2026 Program total $1.9M

• ROSES25: A.15 Biosphere

  NASA Headquarters · NNH25ZDA001N-BIOS

  Open
  Closes Nov 6, 2026

• BJA FY 2026 Tribal Civil and Criminal Legal Assistance

  Bureau of Justice Assistance · O-BJA-2026-172775

  Open
  Closes Nov 6, 2026 Award up to $600,000

• Single Source for the Continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Center (Collaborative U01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DK-27-112

  Open
  Closes Nov 9, 2026 Program total $6.3M

• Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)

  National Institutes of Health · RFA-DK-27-139

  Open
  Closes Nov 9, 2026 Program total $1.8M

• Fiscal Year (FY) 2026 Funding Opportunity for Indian Tribes and Intertribal Consortia for Nonpoint Source Management Grants Under Clean Water Act Section 319

  Environmental Protection Agency · EPA-OW-OWOW-26-01

  Open
  Closes Nov 9, 2026 Award up to $175,000 Program total $3.5M

• Balanced Prosecution of Transnational Organized Crime Cases

  Bureau of International Narcotics-Law Enforcement · OFOP0003790

  Open
  Closes Nov 9, 2026 Award up to $1,100,000 Program total $1.1M

• Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

  National Institutes of Health · RFA-NS-26-001

  Open
  Closes Nov 10, 2026 Program total $40M

• Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-CA-27-002

  Open
  Closes Nov 10, 2026 Award up to $300,000 Program total $5.9M

• Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-CA-27-001

  Open
  Closes Nov 10, 2026 Award up to $150,000 Program total $5.1M

• ROSES25: C.4 Planetary Science Enabling Facilities

  NASA Headquarters · NNH25ZDA001N-PSEF

  Open
  Closes Nov 10, 2026

• Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

  National Institutes of Health · RFA-OD-27-009

  Open
  Closes Nov 10, 2026 Program total $5M

• Capacity Building Grants for Non-Land-Grant Colleges of Agriculture Program

  National Institute of Food and Agriculture · USDA-NIFA-NLGCA-011938

  Open
  Closes Nov 10, 2026 Award up to $750,000 Program total $5.7M

• Clinical Research Network on Antimicrobial Resistance (UM1 Clinical Trial Required)

  National Institutes of Health · RFA-AI-27-005

  Open
  Closes Nov 10, 2026 Program total $18M

• Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)

  National Institutes of Health · RFA-AI-27-002

  Open
  Closes Nov 10, 2026 Program total $10M

• Data Coordinating Center for the Aging and Alzheimer’s Disease Mouse Brain Atlas (AD-MBA) (U24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-AG-27-010

  Open
  Closes Nov 10, 2026 Program total $2.5M

• PFE: Research Initiation in Engineering Formation (PFE: RIEF)

  U.S. National Science Foundation · 20-558

  Open
  Closes Nov 10, 2026 Program total $3M

• FY 2027 COPS-OJP Constitutional Protections for Parents - A NASRO SRO TTA Invitational Program

  Community Oriented Policing Services · O-COPS-2027-172808

  Open
  Closes Nov 10, 2026 Award up to $3,000,000 Program total $3M

• DoW Spinal Cord Injury, Clinical Translation Research Award

  Defense Health Agency Contracting Activity - DHACA · HT942526SCIRPCTRA

  Open
  Closes Nov 12, 2026 Program total $6.1M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.