Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)

  National Institutes of Health · PAR-27-064

  Open
  Closes Jul 5, 2029

• NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-058

  Open
  Closes Jul 5, 2029 Award up to $500,000

• Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-27-072

  Open
  Closes Jul 5, 2029 Award up to $500,000

• Academic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-062

  Open
  Closes Jul 12, 2029

• Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

  National Institutes of Health · PA-27-030

  Open
  Closes Jul 12, 2029

• Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)

  National Institutes of Health · PAR-27-074

  Open
  Closes Jul 16, 2029

• Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)

  National Institutes of Health · PAR-28-093

  Open
  Closes Jul 16, 2029 Award up to $450,000

• Research and Development (RAD) Directed Energy (RD) University Assistance Instruments

  Air Force -- Research Lab · RDK-RAD-FOA-2024

  Open
  Closes Jul 18, 2029 Award up to $49,000,000

• Air Force Basic Research Sciences Conference and Workshop Support

  Air Force Office of Scientific Research · FA955026S0002

  Open
  Closes Aug 31, 2029 Award up to $2,000,000

• Automated Processes for Knowledge Discovery and Information Retrieval

  Air Force -- Research Lab · FA875024S7006

  Open
  Closes Sep 9, 2029 Award up to $99,000,000

• Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)

  National Institutes of Health · PAR-28-022

  Open
  Closes Sep 25, 2029 Program total $1.4M

• Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

  National Institutes of Health · PAR-27-003

  Open
  Closes Sep 26, 2029

• SEEDING CRITICAL ADVANCES FOR LEADING ENERGY TECHNOLOGIES WITH UNTAPPED POTENTIAL (SCALEUP) READY

  Advanced Research Projects Agency Energy · DE-FOA-0003467

  Open
  Closes Sep 29, 2029 Award up to $20,000,000

• FY 2027 - 2029 Broad Agency Announcement (BAA), Oceanic and Atmospheric Research (OAR)

  DOC NOAA - ERA Production · NOAA-OAR-BAA-2027-33939

  Open
  Closes Sep 30, 2029

• Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (RP1 Clinical Trials Optional)

  National Institutes of Health · PAR-28-014

  Open
  Closes Oct 11, 2029

• Pancreatic Cancer Detection Consortium: Research Units (U01 Clinical Trial Optional)

  National Institutes of Health · PAR-28-056

  Open
  Closes Nov 5, 2029 Award up to $600,000

• Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-27-090

  Open
  Closes Nov 5, 2029

• NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-28-072

  Open
  Closes Nov 16, 2029

• Assessing the Feasibility of Incorporating Mechanisms in Multi-site Clinical Trials of Mind and Body Interventions on Whole Person Health Restoration (R33 Clinical Trial Required)

  National Institutes of Health · PAR-28-091

  Open
  Closes Nov 16, 2029 Award up to $500,000

• Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-28-042

  Open
  Closes Nov 16, 2029

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.