Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System

  National Institutes of Health · RFA-NS-28-006

  Upcoming
  Closes Jan 28, 2027 Program total $10M

• NIDDK Multi-Purpose Resource-Related, Multi-Component Research Services Centers Cooperative Agreement (U2C - Clinical Trial Optional)

  National Institutes of Health · RFA-DK-28-114

  Upcoming
  Closes Jan 28, 2027 Program total $9M

• Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

  National Institutes of Health · RFA-ES-28-002

  Upcoming
  Closes Jan 29, 2027 Award up to $2,000,000 Program total $18M

• Health and Extreme Weather Research Coordination and Data Center (U2C - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-ES-28-003

  Upcoming
  Closes Jan 29, 2027 Program total $3M

• NIOSH Mentored Research Scientist Development Award (K01)

  Centers for Disease Control and Prevention - ERA · RFA-OH-27-078

  Upcoming
  Closes Jan 29, 2027 Award up to $100,000 Program total $500K

• KUH P30 Resource Core Center (P30 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DK-28-312

  Upcoming
  Closes Jan 30, 2027

• KUH U24 Center Coordinating Hub (U24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DK-28-313

  Upcoming
  Closes Jan 30, 2027

• RNomics Outreach and Coordination (ROC) Center

  National Institutes of Health · RFA-RM-28-008

  Upcoming
  Closes Feb 1, 2027 Program total $3.5M

• National Urban Indian Health Program (Education and Research)

  Indian Health Service · HHS-2027-IHS-NUIBH-0001

  Upcoming
  Closes Feb 1, 2027 Program total $200K

• Urban Indian Health 4-in-1 Program

  Indian Health Service · HHS-2027-IHS-UIHP2-0001

  Upcoming
  Closes Feb 1, 2027 Program total $9.7M

• Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)

  Centers for Disease Control and Prevention - ERA · RFA-TS-27-018

  Upcoming
  Closes Feb 1, 2027 Award up to $500,000 Program total $4.5M

• Early Detection, Response, and Control of Global Rabies Outbreaks and Associated Threats to America's Dog-Rabies Free Status

  Centers for Disease Control and Prevention - ERA · RFA-CK-27-106

  Upcoming
  Closes Feb 1, 2027 Award up to $400,000 Program total $2M

• RNomics Technology Enhancement Centers

  National Institutes of Health · RFA-RM-28-005

  Upcoming
  Closes Feb 1, 2027 Award up to $2,000,000 Program total $12M

• University Centers for Developmental Disabilities in Educaction, Research, and Service

  Administration for Community Living · HHS-2027-ACL-AOD-DDUC-0001

  Upcoming
  Closes Feb 1, 2027 Award up to $629,042 Program total $26.4M

• CDC National Centers of Excellence in Youth Violence Prevention (YVPCs): Rigorous Evaluation of Prevention Approaches to Prevent and Reduce Youth Violence

  Centers for Disease Control and Prevention - ERA · RFA-CE-27-013

  Upcoming
  Closes Feb 1, 2027 Award up to $1,200,000 Program total $30M

• Preventing Suicide and Interpersonal Violence Among Youth and Young Adults

  Centers for Disease Control and Prevention - ERA · RFA-CE-27-015

  Upcoming
  Closes Feb 1, 2027 Award up to $500,000 Program total $12M

• Rigorously Evaluating Approaches to Prevent Child Sexual Abuse and Problematic Sexual Behavior among Youth

  Centers for Disease Control and Prevention - ERA · RFA-CE-27-016

  Upcoming
  Closes Feb 1, 2027 Award up to $400,000 Program total $4.8M

• Improving Linkage to Care for People with Opioid Use Disorder (U01)

  Centers for Disease Control and Prevention - ERA · RFA-CE-27-017

  Upcoming
  Closes Feb 1, 2027 Award up to $550,000 Program total $11.2M

• Research Grants to Rigorously Evaluate Innovative and Promising Approaches to Prevent Firearm-Related Violence and Injuries

  Centers for Disease Control and Prevention - ERA · RFA-CE-27-014

  Upcoming
  Closes Feb 1, 2027 Award up to $650,000 Program total $13.5M

• Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding

  Health Resources and Services Administration · HRSA-27-068

  Upcoming
  Closes Feb 2, 2027 Award up to $200,000 Program total $3M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.