Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional)

  National Institutes of Health · RFA-DK-28-112

  Upcoming
  Closes Jun 1, 2027 Program total $28M

• Single Source: Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes: Data Resource and Administrative Coordination Center (U24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-MH-28-115

  Upcoming
  Closes Jun 1, 2027 Program total $2.5M

• Clinical Data, Safety and Statistical Centers (CDSSC)

  National Institutes of Health · RFA-AI-28-006

  Upcoming
  Closes Jun 1, 2027 Program total $27.1M

• National Viral Hepatitis Education, Awareness, and Capacity Building for Communities and Providers

  Centers for Disease Control - NCHHSTP · CDC-RFA-PS-27-0011

  Upcoming
  Closes Jun 1, 2027 Program total $5.5M

• Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-CA-28-002

  Upcoming
  Closes Jun 4, 2027 Award up to $300,000 Program total $6.6M

• Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-CA-28-001

  Upcoming
  Closes Jun 4, 2027 Award up to $150,000 Program total $5.4M

• Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

  National Institutes of Health · RFA-DA-28-001

  Upcoming
  Closes Jun 8, 2027 Award up to $1,000,000 Program total $5M

• BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research

  National Institutes of Health · RFA-MH-28-110

  Upcoming
  Closes Jun 10, 2027 Program total $12M

• Immune Drivers of Autoimmune Disease

  National Institutes of Health · RFA-AI-28-011

  Upcoming
  Closes Jun 11, 2027 Program total $3.6M

• Advanced Development and Sustainment of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

  National Institutes of Health · RFA-CA-28-003

  Upcoming
  Closes Jun 11, 2027 Award up to $600,000 Program total $4.4M

• INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-117

  Upcoming
  Closes Jun 15, 2027

• Centers for Research on Neglected Infectious Diseases

  National Institutes of Health · RFA-AI-28-020

  Upcoming
  Closes Jun 15, 2027 Program total $4.2M

• Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development

  National Institutes of Health · PAR-28-043

  Upcoming
  Closes Jun 16, 2027

• Limited Competition: BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships

  National Institutes of Health · RFA-NS-28-005

  Upcoming
  Closes Jun 17, 2027

• Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

  National Institutes of Health · RFA-AG-28-009

  Upcoming
  Closes Jun 18, 2027

• Somatic Mosaicism across Human Tissues (SMaHT) Program: Experimental and Computational Technology Development (RM1 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-RM-28-017

  Upcoming
  Closes Jul 1, 2027

• Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (R24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-RM-28-014

  Upcoming
  Closes Jul 1, 2027

• Somatic Mosaicism across Human Tissues (SMaHT) Program: National Somatic Mosaicism Commons Data Analysis & Organizational Center (UM1 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-RM-28-016

  Upcoming
  Closes Jul 1, 2027

• Somatic Mosaicism across Human Tissues (SMaHT) Program: Genome Characterization Centers (UM1 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-RM-28-015

  Upcoming
  Closes Jul 1, 2027

• Tribal Epidemiology Centers

  Indian Health Service · HHS-2027-IHS-EPI-0001

  Upcoming
  Closes Jul 1, 2027 Program total $7M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.