Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Tobacco Centers of Regulatory Science (TCORS) (Clinical Trial Optional)

  National Institutes of Health · RFA-OD-28-001

  Upcoming
  Closes Nov 10, 2027

• NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)

  National Institutes of Health · RFA-NS-28-008

  Upcoming
  Closes Jan 25, 2028

• NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)

  National Institutes of Health · RFA-NS-28-003

  Upcoming
  Closes Jan 25, 2028

• Limited Competition: Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program

  National Institutes of Health · PAR-28-050

  Upcoming
  Closes Jan 25, 2028

• Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications (U42 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-28-084

  Upcoming
  Closes Jan 25, 2028 Award up to $900,000

• Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program

  National Institutes of Health · PAR-29-004

  Upcoming
  Closes Jan 27, 2028

• ancient DNA for Modern Genomics (aDMG) Research Projects (U01 Clinical Trials Not Allowed)

  National Institutes of Health · RFA-HG-28-003

  Upcoming
  Closes Feb 1, 2028

• Technology Development Program

  National Institutes of Health · PAR-29-005

  Upcoming
  Closes Feb 5, 2028

• Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-29-002

  Upcoming
  Closes Feb 16, 2028 Award up to $500,000

• Public Health Nursing

  Indian Health Service · HHS-2027-IHS-PHN-0001

  Upcoming
  Closes May 1, 2028 Program total $1.5M

• NIDCD Research Fellowship for Audiologists

  National Institutes of Health · PAR-28-013

  Upcoming
  Closes May 30, 2028

• Residential Treatment for Pregnant and Postpartum Women

  Substance Abuse and Mental Health Services Adminis · TI-27-002

  Upcoming
  Expected posting Dec 15, 2026 Program total $12M

• Providers Clinical Support System – Universities

  Substance Abuse and Mental Health Services Adminis · TI-27-001

  Upcoming
  Expected posting Dec 15, 2026 Program total $5M

• GLS Campus Suicide Prevention

  Substance Abuse and Mental Health Services Adminis · SM-27-001

  Upcoming
  Expected posting Dec 15, 2026 Program total $1M

• Assisted Outpatient Treatment

  Substance Abuse and Mental Health Services Adminis · SM-27-002

  Upcoming
  Expected posting Dec 15, 2026 Program total $5.3M

• State Pilot Program for Treatment for Pregnant and Postpartum Women

  Substance Abuse and Mental Health Services Adminis · TI-27-003

  Upcoming
  Expected posting Dec 15, 2026 Program total $2.8M

• Children's Mental Health Initiative

  Substance Abuse and Mental Health Services Adminis · SM-27-003

  Upcoming
  Expected posting Dec 15, 2026 Program total $43M

• Emergency Department Alternatives to Opioids Program

  Substance Abuse and Mental Health Services Adminis · TI-27-005

  Upcoming
  Expected posting Dec 15, 2026

• Building Communities of Recovery

  Substance Abuse and Mental Health Services Adminis · TI-27-004

  Upcoming
  Expected posting Dec 15, 2026 Program total $6.3M

• First Responders-Comprehensive Addiction and Recovery Act

  Substance Abuse and Mental Health Services Adminis · TI-27-006

  Upcoming
  Expected posting Dec 15, 2026 Program total $20M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.