Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Landscape Scale Restoration Grant Program for Non-Federal Lands

  Forest Service · USDA-FS-2026-LSR

  Open
  Closes Jan 26, 2027 Award up to $600,000 Program total $11.3M

• Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-268

  Open
  Closes Jan 27, 2027 Award up to $500,000

• Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-260

  Open
  Closes Jan 27, 2027

• Diabetes Research Centers (P30 Clinical Trial Optional)

  National Institutes of Health · RFA-DK-26-310

  Open
  Closes Jan 27, 2027 Award up to $1,000,000 Program total $18.2M

• Specialized Alcohol Research Centers (P50 Clinical trial Optional)

  National Institutes of Health · RFA-AA-28-001

  Open
  Closes Jan 27, 2027 Award up to $1,150,000 Program total $1.5M

• Translational Neural Devices (R61/R33 - Clinical Trial Optional)

  National Institutes of Health · PAR-25-053

  Open
  Closes Jan 28, 2027

• BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-NS-24-031

  Open
  Closes Jan 28, 2027 Award up to $750,000

• ROSES 2025: A.17 Hydrosphere

  NASA Headquarters · NNH25ZDA001N-HYDRO

  Open
  Closes Jan 28, 2027

• Methodology, Measurement, and Statistics (MMS)

  U.S. National Science Foundation · 19-575

  Open
  Closes Jan 28, 2027 Program total $3.8M

• Minor Use Minor Species Development of Drugs (R01)

  Food and Drug Administration · PAR-24-216

  Open
  Closes Jan 29, 2027 Award up to $250,000 Program total $250K

• Immune Tolerance Network (UM1 Clinical Trial Required)

  National Institutes of Health · RFA-AI-28-005

  Open
  Closes Jan 29, 2027 Program total $27M

• Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-AI-28-012

  Open
  Closes Jan 29, 2027 Program total $7M

• Agriculture Innovation Center Grant Program

  Rural Business-Cooperative Service · RBCS-2026-AIC

  Open
  Closes Jan 31, 2027 Award up to $1,000,000 Program total $2.5M

• Training and Employment Guidance Letter (02-26) for FY 2026 Community Project Funding/Congressionally Directed Spending

  Employment and Training Administration · ETA-TEGL-02-26

  Open
  Closes Jan 31, 2027 Award up to $5,320,000 Program total $95.5M

• Cognitive Neuroscience (CogNeuro)

  U.S. National Science Foundation · PD-24-1699

  Open
  Closes Feb 1, 2027

• Developmental Sciences (DS)

  U.S. National Science Foundation · 24-544

  Open
  Closes Feb 1, 2027 Program total $6.5M

• Biological Anthropology Program Senior Research Awards (BA-SR)

  U.S. National Science Foundation · 23-503

  Open
  Closes Feb 1, 2027 Program total $5M

• Established Program to Stimulate Competitive Research (EPSCoR) Basic Research

  National Aeronautics and Space Administration · NNH27ZHA001C

  Open
  Closes Feb 1, 2027 Award up to $750,000 Program total $21M

• George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional)

  National Institutes of Health · RFA-DK-28-314

  Open
  Closes Feb 1, 2027 Award up to $750,000 Program total $5.2M

• USGS Cooperative Landslide Hazard Mapping and Assessment Program Announcement for Fiscal Year 2027

  Geological Survey · G27AS00381

  Open
  Closes Feb 1, 2027 Award up to $150,000 Program total $1M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.