Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)

  National Institutes of Health · PAR-25-210

  Open
  Closes Jun 2, 2027

• Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

  National Institutes of Health · PAR-25-211

  Open
  Closes Jun 2, 2027

• NEA Arts and Artifacts Domestic Indemnity Program 2, FY2027 (6/27)

  National Endowment for the Arts · 2027FCAHDOM02

  Open
  Closes Jun 7, 2027 Award up to $100,000

• Authority to Accept Unsolicited Proposals for Research Partnerships Notice of Intent (NOI)

  Department of Housing and Urban Development · PDR-2600-DC-0USP

  Open
  Closes Jun 9, 2027 Program total $2M

• NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-416

  Open
  Closes Jun 14, 2027

• BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)

  National Institutes of Health · RFA-MH-26-140

  Open
  Closes Jun 15, 2027

• BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-MH-26-120

  Open
  Closes Jun 15, 2027

• Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)

  National Institutes of Health · RFA-DC-26-001

  Open
  Closes Jun 17, 2027 Program total $1M

• Information Processing Techniques Office Office-Wide

  DARPA - Information Processing Technologies Office · HR001126S0011

  Open
  Closes Jun 22, 2027

• Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-TR-25-002

  Open
  Closes Jul 2, 2027

• APEX Accelerator-Option Period for Existing Award Recipients

  ACC-APG-Aberdeen Division A · DOW2027APEXACCELERATORCLOSED

  Open
  Closes Jul 4, 2027 Award up to $1,500,000

• Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

  National Institutes of Health · PA-24-254

  Open
  Closes Jul 12, 2027

• NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)

  National Institutes of Health · PAR-24-211

  Open
  Closes Jul 12, 2027

• NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-209

  Open
  Closes Jul 12, 2027

• Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

  National Institutes of Health · PA-24-253

  Open
  Closes Jul 17, 2027

• EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (E-CORE)

  U.S. National Science Foundation · 25-523

  Open
  Closes Jul 20, 2027 Program total $37.5M

• Integrated Data Systems & Services (IDSS)

  U.S. National Science Foundation · 26-509

  Open
  Closes Jul 27, 2027 Award up to $30,000,000 Program total $60M

• Expeditions in Computing (Expeditions)

  U.S. National Science Foundation · 26-525

  Open
  Closes Jul 27, 2027 Program total $60M

• Faculty Early Career Development Program (CAREER)

  U.S. National Science Foundation · 22-586

  Open
  Closes Jul 28, 2027 Program total $250M

• EPSCoR Research Infrastructure Improvement Program: EPSCoR Research Incubators for STEM Excellence (E-RISE)

  U.S. National Science Foundation · 25-522

  Open
  Closes Aug 10, 2027 Program total $31.5M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.