Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

  National Institutes of Health · PAR-25-101

  Open
  Closes Aug 11, 2027 Award up to $150,000 Program total $150K

• Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

  National Institutes of Health · PAR-24-293

  Open
  Closes Aug 18, 2027

• Research Experiences for Undergraduates (REU)

  U.S. National Science Foundation · 23-601

  Open
  Closes Aug 18, 2027 Award up to $500,000 Program total $84.8M

• WaterSMART: Desalination Construction Projects

  Bureau of Reclamation · R26AS00034

  Open
  Closes Aug 26, 2027 Award up to $120,000,000 Program total $120M

• Title XVI Water Reclamation and Reuse Projects

  Bureau of Reclamation · R26AS00079

  Open
  Closes Aug 26, 2027 Award up to $40,000,000 Program total $40M

• Defense Sciences Office (DSO) Office-wide BAA

  DARPA - Defense Sciences Office · HR001126S0015

  Open
  Closes Aug 27, 2027

• US Army Combat Capabilities Development Command (DEVCOM) Indo-Pacific Fundamental Research Collaboration Opportunities

  USAF 347 Contracting Squadron · FA520922S0001

  Open
  Closes Aug 30, 2027

• Innovative Traffic Safety Enforcement (ITSE) Grant Program

  National Highway Traffic Safety Administration · NHTSA-693JJ926R000024-FY26

  Open
  Closes Sep 1, 2027 Award up to $20,000,000 Program total $20M

• Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-112

  Open
  Closes Sep 7, 2027

• Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-113

  Open
  Closes Sep 7, 2027

• Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)

  National Institutes of Health · PAR-24-325

  Open
  Closes Sep 7, 2027

• Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

  National Institutes of Health · PAR-24-330

  Open
  Closes Sep 7, 2027

• FAA Aviation Research Grants Program

  DOT - FAA Aviation Research Grants · 20-01

  Open
  Closes Sep 7, 2027 Award up to $6,000,000

• NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

  National Institutes of Health · PA-25-080

  Open
  Closes Sep 7, 2027

• WaterSMART Enhancing Water Resources Projects

  Bureau of Reclamation · R26AS00017

  Open
  Closes Sep 8, 2027 Award up to $3,000,000 Program total $60M

• Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-325

  Open
  Closes Sep 10, 2027

• Community Infrastructure for Research in Computer and Information Science and Engineering (CIRC)

  U.S. National Science Foundation · 23-589

  Open
  Closes Sep 10, 2027 Award up to $5,000,000 Program total $24M

• Engineering Research Initiation (ERI)

  U.S. National Science Foundation · 24-590

  Open
  Closes Sep 16, 2027 Program total $11M

• Department of Defense HIV/AIDS Prevention Program

  Defense Health Agency Contracting Activity - DHACA · W81XWH-22-DHAPP

  Open
  Closes Sep 18, 2027

• Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences

  U.S. National Science Foundation · 22-600

  Open
  Closes Sep 20, 2027 Award up to $1,200,000 Program total $5M

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.