Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-301

  Open
  Closes Sep 25, 2027

• Clinical and Translational Science Award (UM1 Clinical Trial Optional)

  National Institutes of Health · PAR-24-272

  Open
  Closes Sep 28, 2027

• Postdoctoral Research Fellowships in Biology (PRFB)

  U.S. National Science Foundation · 26-504

  Open
  Closes Sep 28, 2027 Program total $16.5M

• Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-020

  Open
  Closes Sep 29, 2027 Award up to $250,000

• CHEERS Open Period 1 - All Technical Areas

  Air Force -- Research Lab · FA238424S2334

  Open
  Closes Sep 30, 2027

• CHEERS Open Period 2 - All Technical Areas

  Air Force -- Research Lab · FA238424S2335

  Open
  Closes Sep 30, 2027

• DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research

  Defense Health Agency Contracting Activity - DHACA · HT942523SBAA1

  Open
  Closes Sep 30, 2027

• FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

  Office of Science · DE-FOA-0003665

  Open
  Closes Sep 30, 2027 Award up to $10,000,000 Program total $400M

• U.S. Jordan Private Sector Innovation Fund APS

  Bureau of Near Eastern Affairs · DFOP0020010

  Open
  Closes Sep 30, 2027 Award up to $20,000,000 Program total $50M

• Home Study and Post-Release Services for Unaccompanied Alien Children

  Administration for Children and Families - ORR · HHS-2026-ACF-ORR-ZU-0019

  Open
  Closes Oct 1, 2027 Award up to $100,000,000 Program total $555M

• BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-NS-27-015

  Open
  Closes Oct 4, 2027 Program total $10M

• Advanced Technological Education (ATE)

  U.S. National Science Foundation · 24-584

  Open
  Closes Oct 7, 2027 Award up to $7,500,000 Program total $74M

• Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-248

  Open
  Closes Oct 8, 2027

• Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)

  National Institutes of Health · PAR-25-327

  Open
  Closes Oct 8, 2027

• NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

  National Institutes of Health · RFA-DC-25-002

  Open
  Closes Oct 12, 2027 Award up to $500,000 Program total $500K

• Research Experiences for Teachers (RET) in Engineering and Computer Science

  U.S. National Science Foundation · 24-503

  Open
  Closes Oct 13, 2027 Program total $5.8M

• NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-135

  Open
  Closes Oct 14, 2027

• NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)

  National Institutes of Health · PAR-25-313

  Open
  Closes Oct 14, 2027

• Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

  National Institutes of Health · PAR-25-183

  Open
  Closes Oct 15, 2027

• Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

  National Institutes of Health · PAR-25-285

  Open
  Closes Oct 15, 2027

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.