Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)

  National Institutes of Health · PAR-25-177

  Open
  Closes Oct 15, 2027

• Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)

  National Institutes of Health · PAR-25-181

  Open
  Closes Oct 15, 2027

• Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

  National Institutes of Health · PAR-25-178

  Open
  Closes Oct 15, 2027

• Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)

  National Institutes of Health · PAR-25-179

  Open
  Closes Oct 15, 2027

• Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)

  National Institutes of Health · PAR-25-182

  Open
  Closes Oct 15, 2027

• First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)

  National Institutes of Health · PAR-25-180

  Open
  Closes Oct 15, 2027

• Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)

  National Institutes of Health · PAR-25-184

  Open
  Closes Oct 15, 2027

• NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)

  National Institutes of Health · PAR-25-120

  Open
  Closes Oct 15, 2027

• NSF Astronomy and Astrophysics Postdoctoral Fellowships (AAPF)

  U.S. National Science Foundation · 22-621

  Open
  Closes Oct 15, 2027 Program total $990K

• NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-357

  Open
  Closes Oct 16, 2027

• NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)

  National Institutes of Health · PAR-25-343

  Open
  Closes Oct 18, 2027

• Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

  National Institutes of Health · RFA-CA-27-019

  Open
  Closes Oct 19, 2027 Award up to $300,000 Program total $2.4M

• Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR)

  U.S. National Science Foundation · 23-598

  Open
  Closes Oct 19, 2027 Program total $28M

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-225

  Open
  Closes Oct 20, 2027

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-059

  Open
  Closes Oct 20, 2027 Award up to $750,000 Program total $750K

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-060

  Open
  Closes Oct 20, 2027 Award up to $750,000 Program total $750K

• Mathematical Sciences Postdoctoral Research Fellowships (MSPRF)

  U.S. National Science Foundation · 23-603

  Open
  Closes Oct 20, 2027 Program total $8.5M

• Pilot Projects to Enhance the Human Virome Program (R03 Clinical Trials Not Allowed)

  National Institutes of Health · RFA-RM-27-024

  Open
  Closes Oct 22, 2027 Award up to $100,000 Program total $2M

• Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)

  National Institutes of Health · PAR-25-103

  Open
  Closes Oct 25, 2027

• Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)

  National Institutes of Health · PAR-25-104

  Open
  Closes Oct 25, 2027

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.