Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DA-26-034

  Open
  Closes Nov 18, 2027 Award up to $300,000 Program total $300K

• DEVCOM ARMY RESEARCH LABORATORY BROAD AGENCY ANNOUNCEMENT FOR FOUNDATIONAL RESEARCH

  Dept of the Army -- Materiel Command · W911NF-23-S-0001

  Open
  Closes Nov 20, 2027

• Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DA-26-055

  Open
  Closes Dec 3, 2027

• Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-DA-26-056

  Open
  Closes Dec 3, 2027

• Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-HL-26-019

  Open
  Closes Dec 23, 2027

• Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-HL-26-020

  Open
  Closes Dec 23, 2027

• Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)

  National Institutes of Health · RFA-HL-26-016

  Open
  Closes Dec 23, 2027 Award up to $350,000

• Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-HL-26-018

  Open
  Closes Dec 23, 2027

• Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)

  National Institutes of Health · RFA-HL-26-017

  Open
  Closes Dec 23, 2027

• NPS Cooperative Ecosystems Studies Units (CESU) Master Cooperative Agreements

  National Park Service · P23AS00132

  Open
  Closes Dec 31, 2027

• DEVCOM ANALYSIS CENTER BROAD AGENCY ANNOUNCEMENT FOR APPLIED RESEARCH

  Dept of the Army -- Materiel Command · W911NF-23-S-0003

  Open
  Closes Jan 4, 2028

• NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

  National Institutes of Health · PAR-25-188

  Open
  Closes Jan 6, 2028 Award up to $500,000

• NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

  National Institutes of Health · PAR-25-057

  Open
  Closes Jan 6, 2028

• Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAS-25-205

  Open
  Closes Jan 6, 2028

• Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

  National Institutes of Health · PAR-25-062

  Open
  Closes Jan 6, 2028

• Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-144

  Open
  Closes Jan 7, 2028

• Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

  National Institutes of Health · PAR-25-143

  Open
  Closes Jan 7, 2028

• Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-233

  Open
  Closes Jan 7, 2028

• Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-286

  Open
  Closes Jan 7, 2028

• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-298

  Open
  Closes Jan 7, 2028 Award up to $375,000

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.