Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Focused Technology Research and Development (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-203

  Open
  Closes Jan 7, 2028

• Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-227

  Open
  Closes Jan 7, 2028

• Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-145

  Open
  Closes Jan 7, 2028

• Laboratories to Optimize Digital Health (R01 Clinical Trial Required)

  National Institutes of Health · PAR-25-136

  Open
  Closes Jan 7, 2028

• Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-273

  Open
  Closes Jan 7, 2028 Award up to $200,000 Program total $200K

• NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-027

  Open
  Closes Jan 7, 2028

• Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-043

  Open
  Closes Jan 7, 2028 Award up to $500,000

• Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

  National Institutes of Health · PAR-25-024

  Open
  Closes Jan 7, 2028

• Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-281

  Open
  Closes Jan 7, 2028

• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)

  National Institutes of Health · PAR-25-148

  Open
  Closes Jan 7, 2028

• Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-24-311

  Open
  Closes Jan 7, 2028 Award up to $500,000 Program total $500K

• NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-251

  Open
  Closes Jan 7, 2028 Award up to $150,000 Program total $150K

• Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

  National Institutes of Health · PAR-25-207

  Open
  Closes Jan 7, 2028

• NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-105

  Open
  Closes Jan 7, 2028

• NICHD Small Research Grant Program (R03 Clinical Trial Required)

  National Institutes of Health · PA-25-125

  Open
  Closes Jan 7, 2028 Award up to $50,000 Program total $50K

• Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-175

  Open
  Closes Jan 7, 2028 Award up to $500,000 Program total $500K

• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-134

  Open
  Closes Jan 7, 2028 Award up to $375,000

• Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

  National Institutes of Health · PAR-25-291

  Open
  Closes Jan 7, 2028 Award up to $200,000 Program total $200K

• Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)

  National Institutes of Health · PAR-25-288

  Open
  Closes Jan 7, 2028

• Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)

  National Institutes of Health · PA-25-172

  Open
  Closes Jan 7, 2028

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.