Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-OD-27-004

  Open
  Closes Jun 15, 2028 Award up to $500,000 Program total $3M

• INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)

  National Institutes of Health · RFA-OD-27-005

  Open
  Closes Jun 15, 2028 Program total $3M

• INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-OD-27-003

  Open
  Closes Jun 15, 2028 Award up to $200,000 Program total $1M

• Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)

  National Institutes of Health · PAR-27-053

  Open
  Closes Jun 16, 2028

• BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-NS-27-002

  Open
  Closes Jun 23, 2028 Award up to $8,000,000 Program total $1M

• Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-021

  Open
  Closes Jul 1, 2028 Award up to $400,000

• Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-022

  Open
  Closes Jul 1, 2028 Award up to $5,000,000

• Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)

  National Institutes of Health · PAR-27-076

  Open
  Closes Jul 7, 2028 Award up to $499,000

• Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional)

  National Institutes of Health · PAR-27-096

  Open
  Closes Jul 16, 2028 Award up to $125,000

• Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-450

  Open
  Closes Jul 20, 2028

• BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense

  Defense Health Agency Contracting Activity - DHACA · HT9425-23-S-SOC1

  Open
  Closes Jul 31, 2028 Award up to $50,000,000 Program total $10M

• Defense Security Cooperation University - Research Grants

  Washington Headquarters Services · HQ003423NFOEASD17

  Open
  Closes Aug 7, 2028 Award up to $800,000

• Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)

  National Institutes of Health · PAR-25-446

  Open
  Closes Aug 21, 2028 Award up to $3,000,000

• Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)

  National Institutes of Health · RFA-DC-27-003

  Open
  Closes Aug 21, 2028 Award up to $500,000 Program total $2M

• Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-25-322

  Open
  Closes Aug 25, 2028

• Vet-LIRN Capacity-Building Project and Equipment Grants (U18)

  Food and Drug Administration · PAR-23-202

  Open
  Closes Sep 4, 2028 Award up to $2,500,000

• Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)

  National Institutes of Health · PA-25-253

  Open
  Closes Sep 7, 2028

• Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)

  National Institutes of Health · PAR-25-324

  Open
  Closes Sep 7, 2028

• NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)

  National Institutes of Health · PAR-26-033

  Open
  Closes Sep 25, 2028

• Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

  National Institutes of Health · PAR-25-444

  Open
  Closes Sep 25, 2028

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.