Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)

  National Institutes of Health · PAR-27-026

  Open
  Closes Sep 25, 2028

• Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-OD-25-011

  Open
  Closes Sep 26, 2028 Program total $1.3M

• Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)

  National Institutes of Health · RFA-OD-25-010

  Open
  Closes Sep 28, 2028 Program total $5M

• FY 2027 – 2029 Broad Agency Announcement (BAA), National Marine Fisheries Service

  DOC NOAA - ERA Production · NOAA-NMFS-FHQ-2027-33600

  Open
  Closes Sep 30, 2028

• FY 2027-2028 NESDIS Broad Agency Announcement (BAA)

  DOC NOAA - ERA Production · NOAA-NESDIS-NESDISPO-2027-33921

  Open
  Closes Sep 30, 2028

• FY 2026 - 2028 Broad Agency Announcement (BAA), National Ocean Service

  DOC NOAA - ERA Production · NOAA-NOS-MB-2027-33927

  Open
  Closes Sep 30, 2028 Award up to $100

• Limited Competition: NIGMS Mature Synchrotron Resources (MSR) for Structural Biology (P30 - Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-068

  Open
  Closes Oct 2, 2028

• BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-NS-27-001

  Open
  Closes Oct 6, 2028 Program total $10M

• Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-AI-27-014

  Open
  Closes Oct 9, 2028

• Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)

  National Institutes of Health · RFA-NS-28-012

  Open
  Closes Oct 10, 2028 Award up to $2,500,000 Program total $6M

• Limited Competition: Stimulating Access to Research in Residency Transition Scholar (StARRTS) (K38 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-HL-27-010

  Open
  Closes Oct 13, 2028 Award up to $6,444,000 Program total $10.8M

• Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research (R21 CT Not Allowed)

  National Institutes of Health · RFA-HD-27-007

  Open
  Closes Oct 20, 2028 Award up to $200,000 Program total $1M

• Occupational Safety and Health Education and Research Centers (T42)

  Centers for Disease Control and Prevention - ERA · RFA-OH-25-002

  Open
  Closes Oct 26, 2028 Award up to $9,000,000 Program total $32M

• Occupational Safety and Health Training Project Grants (T03)

  Centers for Disease Control and Prevention - ERA · RFA-OH-25-003

  Open
  Closes Oct 26, 2028 Award up to $550,000 Program total $24M

• Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)

  National Institutes of Health · PAR-27-013

  Open
  Closes Nov 2, 2028

• Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)

  National Institutes of Health · PAR-27-012

  Open
  Closes Nov 2, 2028

• Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

  National Institutes of Health · PAR-27-011

  Open
  Closes Nov 2, 2028

• Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-25-362

  Open
  Closes Nov 5, 2028 Award up to $400,000

• CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-075

  Open
  Closes Nov 5, 2028 Award up to $300,000

• Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

  National Institutes of Health · RFA-HL-27-004

  Open
  Closes Nov 7, 2028 Award up to $85,000 Program total $3.9M

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