Federal grant opportunities open to nonprofits

Grants.gov listings that name nonprofits as eligible applicants. We re-check every listing daily and mark an opportunity Open only when Grants.gov confirmed it within the last 48 hours.

816 open, 304 upcoming · last checked Nov 5, 2026 · 1,120 shown by this search.

• Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)

  National Institutes of Health · PAR-27-015

  Open
  Closes Nov 16, 2028 Award up to $300,000

• The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-26-134

  Open
  Closes Nov 22, 2028 Award up to $500,000

• Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

  National Institutes of Health · PA-26-001

  Open
  Closes Nov 30, 2028

• FOUNDATIONS OF TRUSTED SYSTEMS

  Air Force -- Research Lab · FA875025S7001

  Open
  Closes Dec 5, 2028 Award up to $99,900,000

• Updated National Dislocated Worker Grant Program Guidance and Application Information

  Employment and Training Administration · ETA-TEGL-09-24-CH1

  Open
  Closes Dec 31, 2028 Award up to $10,000,000 Program total $300M

• Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-067

  Open
  Closes Jan 26, 2029 Award up to $250,000

• Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-024

  Open
  Closes Jan 29, 2029

• Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)

  National Institutes of Health · PAR-27-032

  Open
  Closes Feb 6, 2029

• BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed)

  National Institutes of Health · RFA-NS-28-010

  Open
  Closes Feb 8, 2029 Program total $8M

• HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)

  National Institutes of Health · RFA-DA-27-016

  Open
  Closes Feb 9, 2029

• HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

  National Institutes of Health · RFA-NS-27-007

  Open
  Closes Feb 20, 2029 Program total $11M

• NCI Research Specialist (Clinician Scientist) Award (R50 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-28-063

  Open
  Closes Feb 20, 2029

• NIAMS P30 Centers Program (P30 - Clinical Trial Not Allowed)

  National Institutes of Health · RFA-AR-28-001

  Open
  Closes Mar 1, 2029 Award up to $500,000 Program total $17M

• Research Grants in Clinical Informatics (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-26-042

  Open
  Closes Mar 5, 2029 Award up to $250,000 Program total $2.5M

• Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)

  National Institutes of Health · PAR-26-040

  Open
  Closes Mar 5, 2029 Award up to $250,000 Program total $2.5M

• NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)

  National Institutes of Health · PAR-27-065

  Open
  Closes Mar 9, 2029

• Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Not Allowed)

  National Institutes of Health · PAR-27-025

  Open
  Closes Mar 12, 2029

• Mathematical Sciences Research Institutes

  U.S. National Science Foundation · 23-606

  Open
  Closes Mar 14, 2029 Award up to $6,500,000 Program total $40M

• Science Track Award for Research Transition (START) Program (R03, Clinical Trial Optional)

  National Institutes of Health · PAS-27-028

  Open
  Closes Mar 16, 2029

• ARMY APPLICATIONS LAB BROAD AGENCY ANNOUNCEMENT FOR DISRUPTIVE APPLICATIONS

  Dept of the Army -- Materiel Command · W911NF-24-S-0008

  Open
  Closes Apr 4, 2029

Source: Grants.gov. Grantvello is not affiliated with Grants.gov or any federal agency. Always read the full notice of funding opportunity on Grants.gov before applying.